PROGRAMME GROUP HUMANS, ENVIRONMENT, TECHNOLOGY (MUT)
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ProjectTaskExpert Opinions Results
Summary and results of the first workshop on 10 July 2001 at the Research Centre for Electromagnetic Environmental Compatibility, Aachen
  1. Following a short introduction and explanation of the project goals MUT presented and discussed a first evaluation of the agreements and differences in the data base (literature) of the four experts.
  2. The experts subsequently explained their procedure and their criteria for selecting the literature.
  3. The experts then briefly presented the essential results of their expert opinions with respect to risk assessment and the underlying arguments.
  4. Based on a compilation of the end points dealt with in the expert opinions and of the experts' topics and representation of results, a structured list of end points and topics was generated, which is shown in the table below.
  5. This list was discussed with a view to the essential points of dissent among the experts. The participants then agreed on a selection of end points and topics (these are underlined in the table), for which the differences were apparent. These will be dealt with in detail at the next three workshops (in September, October and November) calling upon further external experts.

    End Points and Topics
    Triggering and promoting carcinogenesis, teratogenesis, mutagenesis
      Gene toxicity and transformation
      Chromosome mutation and aberration / DNA nicks
      Gene mutation and gene expression
      Cell proliferation
      Reproduction and evolution
      Studies on the carcinogenesis in animals
     
    Epidemiological studies on humans
    CNS
      calcium homeostasis / calcium metabolism
      Neurotransmitters
      Neuroendocrine system and hormones (melatonin)
      Stress hormones
      Neurodegenerative diseases / Alzheimer's
      Blood-brain barrier
      Sensory receptors
    Cognitive functionsognitive Funktionen
      Brain function / EEG
      Sleeping behaviour
      Cognitive abilities / learning behaviour / attention
    Other pathophysiological effect
      Enzyme production / gene transcription and gene translation
      Cardiovascular system
    Implants

  6. The methodological basis for further procedure at the workshops should be the approach of evidence-based medicine, especially the report by the Australian National Health and Medical Research Council: "How to use the evidence: assessment and application of scientific evidence" (available online at: http://www.nhmrc.health.gov.au/publications/pdf/cp69.pdf)1.
  7. The external experts should comment on the individual end points and topics with respect to the following three priorities: - assessment of the scientific quality of the primary studies used, - significance of the findings to health, - risk assessment for the exposure conditions of base stations and mobile phonesethodische Grundlage für das weitere Vorgehen in den Workshops soll der Ansatz der Evidence Based Medicine bilden, speziell der Report des australischen National Health and Medical Research Council: "How to use the evidence: assessment and application of scientific evidence"
1 see also the other reports by the NHMRC on these topics (http://www.health.gov.au/nhmrc/publications/synopses/cp65syn.htm)
ProjectTaskExpert Opinions Results
Research Center Jülich Imprint Programme Group Humans, Enviroment, Technology (MUT)

Deutsche Version

 23.03.2010
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